MS Relapse vs. Pseudo-Relapse: Key Differences

An MS relapse, also known as an exacerbation or flare-up, occurs when there is new inflammation in the central nervous system (CNS). This inflammation damages the myelin sheath, which protects nerve fibers, causing new symptoms or the worsening of existing ones. To be considered a relapse, the symptoms must last at least 24 hours and should not be related to an infection or other external factors. Relapses can be serious, often leading to the need for medical intervention, such as corticosteroids, to reduce inflammation.
Causes: New CNS inflammation.
Duration: Symptoms last more than 24 hours.
Symptoms: Can involve new or worsened symptoms, such as vision problems, motor difficulties, or cognitive impairment.
Treatment: Often requires medical intervention, including corticosteroids to reduce CNS inflammation and manage symptoms.



True. Infection, stress, and heat play important roles here.